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SASInstitute A00-282 Exam Syllabus Topics:
| Section | Weight | Objectives |
|---|---|---|
| Report Clinical Trials Results | 10% | - PROC REPORT and PROC PRINT - Produce tables, listings, and figures |
| Macro Programming for Clinical Trials | 15% | - Debugging macros - Create and call macros - Macro variables and parameters |
| Apply Statistical Procedures for Clinical Trials | 15% | - Basic statistical analysis for clinical data - PROC MEANS, FREQ, TABULATE |
| Clinical Trials Process | 5% | - Clinical trial lifecycle and protocol - Derive programming requirements from protocol and CRF |
| Transform or Summarize Clinical Trials Data | 15% | - Aggregation and transposition - Derive variables and study days - Data step manipulation |
| Regulatory Submissions | 5% | - Compliance for clinical data reporting - ICH and FDA guidelines |
| Manage Clinical Trials Data | 5% | - Clean, merge, and subset data - Access and explore clinical datasets - Use SQL and dictionary tables |
| Clinical Trials Data Structures | 10% | - Define.xml and dataset specifications - Clinical domain structures - CDISC standards: SDTM, ADaM |
| Validate Clinical Trial Data Reporting | 20% | - Validation principles - Programming validation techniques - Use PROC COMPARE and log review |
SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:
1. Which SAS program will apply the data set label 'Demographics' to the data set named DEMO?
A) data demo;
set demo (label='Demographics');
run;
B) data demo (label='Demographics');
set demo;
run;
C) data demo; set demo;
label demo= 'Demographics';
run;
D) data demo (label 'Demographics');
set demo;
run;
2. Where would you store a value collected on a case report form but not defined in an SDTM domain?
A) DM
B) SC
C) SUPPQUAL
D) RELREC
3. How does the code shown below help to validate report output?
data check;
set datlib.medhist;
mh_len = length(trim(mhcom1));
run;
proc freq data=check;
tables mh_len;
run;
A) It helps the programmer determine which observation has the longest value for mhcom1.
B) It shows all the values for the length of mhcom1 in the results.
C) It writes all values of the mhcom1 variable that are longer than 200 in the results.
D) It shows all the values for mhcom1 in the results.
4. A dataset contains systolic blood pressure values stored in the variable SYSBP.
Which program displays the median systolic blood pressure over all participants?
A) proc summary data=vitals print;
var sysbp;
run;
B) proc univariate data=vitals;
var sysbp;
run;
C) proc freq data=vitals;
tables sysbp;
run;
D) proc means data=vitals;
var sysbp;
run;
5. Which two variables are required in BDS ADaM data sets?
(Choose two.)
A) PARAM
B) AVAL
C) ASEQ
D) STUDYID
Solutions:
| Question # 1 Answer: B | Question # 2 Answer: C | Question # 3 Answer: B | Question # 4 Answer: B | Question # 5 Answer: A,D |







